Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugsOTTON, S. V; INABA, T; KALOW, W et al.Life sciences (1973). 1984, Vol 34, Num 1, pp 73-80, issn 0024-3205Article

Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotypeBROSEN, K; OTTON, S. V; GRAM, L. F et al.Clinical pharmacology and therapeutics. 1986, Vol 40, Num 5, pp 543-549, issn 0009-9236Article

Sparteine oxidation polymorphism: a family studyBROSEN, K; OTTON, S. V; GRAM, L. F et al.British journal of clinical pharmacology. 1986, Vol 21, Num 6, pp 661-667, issn 0306-5251Article

Interactions of amphetamine analogs with human liver CYP2D6WU, D; OTTON, S. V; INABA, T et al.Biochemical pharmacology. 1997, Vol 53, Num 11, pp 1605-1612, issn 0006-2952Article

Cytochrome P450 2D6 and treatment of codeine dependenceROMACH, M. K; OTTON, S. V; SOMER, G et al.Journal of clinical psychopharmacology. 2000, Vol 20, Num 1, pp 43-45, issn 0271-0749Article

Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphismBRØSEN, K; KLYSNER, R; GRAM, L. F et al.European journal of clinical pharmacology. 1986, Vol 30, Num 6, pp 679-684, issn 0031-6970Article

A human cytochrome P-450 characterized by inhibition studies at the sparteine―debrisoquine monooxygenaseINABA, T; NAKANO, M; OTTON, S. V et al.Canadian journal of physiology and pharmacology. 1984, Vol 62, Num 7, pp 86-862, issn 0008-4212Article

Inhibitors of cytochrome P450 differentially modify discriminative-stimulus and antinociceptive effects of hydrocodone and hydromorphone in rhesus monkeysLELAS, S; WEGERT, S; OTTON, S. V et al.Drug and alcohol dependence. 1999, Vol 54, Num 3, pp 239-249, issn 0376-8716Article

Simultaneous gas chromatographic determination of methamphetamine, amphetamine and their p-hydroxylated metabolites in plasma and urineCHEUNG, S; NOLTE, H; OTTON, S. V et al.Journal of chromatography. B, Biomedical sciences and applications. 1997, Vol 690, Num 1-2, pp 77-87, issn 1387-2273Article

Human hepatic cytochrome P450 2D6-like activity in nonhuman primates : catalytic characterization in vitroDAFANG WU; OTTON, S. V; MORROW, P et al.The Journal of pharmacology and experimental therapeutics. 1993, Vol 266, Num 2, pp 715-719, issn 0022-3565Article

Inhibition by fluoxetine of cytochrome P450 2D6 activityOTTON, S. V; DAFANG WU; JOFFE, R. T et al.Clinical pharmacology and therapeutics. 1993, Vol 53, Num 4, pp 401-409, issn 0009-9236Article

Drug metabolism and interactions in abuse liability assessmentSELLERS, E. M; OTTON, S. V; BUSTO, U. E et al.British journal of addiction (1980). 1991, Vol 86, Num 12, pp 1607-1614, issn 0952-0481Conference Paper

Propranolol oxidation by human liver microsomes-the use of cumene hydroperoxide to probe isoenzyme specificity and regio- and stereoselectivityOTTON, S. V; GILLAM, A. M. J; LENNARD, M. S et al.British journal of clinical pharmacology. 1990, Vol 30, Num 5, pp 751-760, issn 0306-5251, 10 p.Article

Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and CaucasiansDROLL, K; BRUCE-MENSAH, K; OTTON, S. V et al.Pharmacogenetics (London). 1998, Vol 8, Num 4, pp 325-333, issn 0960-314XArticle

CYP2D6 inhibition in patients treated with sertralineSPROULE, B. A; OTTON, S. V; CHEUNG, S. W et al.Journal of clinical psychopharmacology. 1997, Vol 17, Num 2, pp 102-106, issn 0271-0749Article

CYP2D6 phenotype determines the metabolic conversion of hydrocodone to hydromorphoneOTTON, S. V; SCHADEL, M; SIU WAH CHEUNG et al.Clinical pharmacology and therapeutics. 1993, Vol 54, Num 5, pp 463-472, issn 0009-9236Article

Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadoneWU, D; OTTON, S. V; SPROULE, B. A et al.British journal of clinical pharmacology. 1993, Vol 35, Num 1, pp 30-34, issn 0306-5251Conference Paper

Catalytic and immunologic and similarities between monkey and human liver cytochrome P-450db1 (human cytochrome P-450 2D6)OTTON, S. V; TYNDALE, R. F; WU, D et al.Drug metabolism and disposition. 1992, Vol 20, Num 1, pp 1-5, issn 0090-9556Article

Characterization of metronidazole metabolism by human liver microsomesLOFT, S; OTTON, S. V; LENNARD, M. S et al.Biochemical pharmacology. 1991, Vol 41, Num 8, pp 1127-1134, issn 0006-2952, 8 p.Article

Sparteine oxidation is practically abolished in quinidine-treated patientsBRINN, R; BRØSEN, K; GRAM, L. F et al.British journal of clinical pharmacology. 1986, Vol 22, Num 2, pp 194-197, issn 0306-5251Article